Thursday, August 23, 2012

SYSTEMIC FUNGI

 Systemic fungi -     Blast His Coccyx
                                           Blast          BLASTOMYCES
                                           His             HISTOPLASMA
                                          Coccyx      COCCIDIODES
              
All systemic fungi are dimorphic
Cold(20) =Mold
Heat (37)=Yeast                            
All systemic fungi cause pneumonia

Blastomyces-      Broad Based Buds
                            Forms Granulomatous nodules 
                                                              

  2nd figure above shows broad based buds with double refractile cell wall (not capsule)   
                                 
 Histoplasma  -   Hides in Macrophages
                           Hepatospleenomegaly
                           Healing Calcifies lesions
histoplasma yeast forms in alveolar macrophages

Histoplasma Macro and Micro conidia

Coccidiodes -  case rate increases after Earth Crack(quake) 
                        Causes Meningitis 
                         Arthroconidia inhaled forms Sperules with                                  
                         Endospores in body 



Histoplasma In Macrophages smaller than RBC 
                             

Blastomyces  buds same size as RBC

Coccidiodes Spherules with endospores much larger than RBC




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